The increase in North Americans breathing smoke from wildfires is proving to be a significant health threat, with predictions indicating a potential rise in wildfire smoke-related deaths. A report suggests that by 2050, wildfire smoke could cause 71,000 deaths, with California being particularly vulnerable. This underlines the urgent need to address the complex relationship between climate change, wildfires, and public health. The impact is not limited to the immediate danger posed by wildfires but extends to the long-term health risks associated with prolonged smoke exposure. These findings highlight the critical importance of implementing effective strategies to mitigate the escalating threat of wildfire smoke, which is exacerbated by the changing climate.